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Treatments for Peptic Ulcer Disease

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The treatment and management of peptic ulcers involves lifestyle changes, medications, alternative and complementary therapies, and surgery. The goals of treatment include:

  • Elimination of Helicobacter pylori infection if present
  • Treating excess bleeding
  • Promoting healing of the ulcer
  • Relieving pain and discomfort
  • Avoiding the development of complications such as perforation, obstruction
  • Preventing ulcer recurrence

Treatment may involve the following:

Lifestyle changesMedicationsAlternative and complementary therapiesSurgery

Revision Information

  • Reviewer: Daus Mahnke, MD
  • Review Date: 03/2014 -
  • Update Date: 05/08/2014 -
  • H. pylori and peptic ulcers. National Digestive Diseases Information Clearinghouse website. Available at: http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/index.aspx. Updated April 30, 2012. Accessed April 29, 2013.

  • Meurer LN, Bower DJ. Management of helicobacter pylori infection. Am Fam Physician. 2002;65(7):1327-36.

  • Peptic ulcer disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated April 22, 2013. Accessed April 29, 2013.

  • Understanding peptic ulcer disease. American Gastroenterological Association website. Available at: http://www.gastro.org/patient-center/digestive-conditions/peptic-ulcer-disease. Published April 23, 2010. Accessed April 29, 2013.